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Some options include creating barriers to protect the cells, or adding oxygen or other agents to the transplant site.ДЇinally, researchers are investigating how to increase the supply of islets available for transplant. Second, they are looking for ways to sustain the isletsвЂ™ long-term survival and protecting them from the autoimmune attack that caused the type 1 diabetes in the first place. Scientists are investigating other possible transplant sites and options, including a bio-engineered platform that acts as an artificial pancreas. While the liver is the traditional site for islet transplantation, this location is not ideal. The BioHub StrategyДRIвЂ™s BioHub strategy is a three-step approach to overcoming the current limitations of islet transplantation.ДЇirst, scientists focus on the transplant site. Now they are working to improve the science so that more people can benefit from this treatment. In studies, some patients who had this procedure have been able to reduce the need for insulin injections, or stop injecting insulin altogether.ДRI scientists have already shown that islet transplantation can eliminate the need for insulin injections. In an islet transplant, doctors take healthy islets from the pancreas of an organ donor, and inject them into someone with type 1 diabetes. Islets are clusters of cells found in the pancreas that work together to regulate blood sugar. This research focuses on a process called islet transplantation. A biological cure means treatment that would help the body start producing its own insulin again, restoring blood sugars to normal levels without introducing other risks. What is a biological cure?ДRI researchers are working toward a biological cure for type 1 diabetes. These trials are already allowing some patients to live insulin-free, significantly improving their quality of life. Now clinical trials are underway for treatments to reverse type 1 diabetes and restore the bodyвЂ™s ability to produce insulin naturally. Thanks to past advancements in medicine, patients are able to control their blood glucose levels with regular insulin injections or an insulin pump. How close are we to a cure?ДЇor a century, treatment for type 1 diabetes has focused on managing the disease. While itвЂ™s most commonly diagnosed in children and young adults, people can develop type 1 diabetes at any age. It is an autoimmune disorder, where the bodyвЂ™s immune system mistakenly attacks and destroys healthy cells in the pancreas. Type 1 diabetes is not caused by a personвЂ™s diet or lifestyle. This can lead to serious or life-threatening complications over time. Without insulin, sugar builds up in the blood and can damage your internal organs, including your heart, kidneys, eyes, nervous system, and other parts of the body. With type 1 diabetes, your pancreas stops making insulin, a hormone that helps the body convert blood sugar into energy.

However, researchers with the Diabetes Research Institute are now working on treatments to reverse the disease, so that people with type 1 diabetes can live healthy lives without medication. One of the first things people ask when theyвЂ™ve been diagnosed with type 1 diabetes is: is there a cure? The truth is, while type 1 diabetes can be managed with insulin, diet and exercise, there is currently no cure.

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